ISSN  2587-2362  |  E-ISSN  2618-642X

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International Journal of Medical Biochemistry The role of serum acute phase reactant level at prediction of impacted ureteral stone [Int J Med Biochem ]
Int J Med Biochem . Ahead of Print: IJMB-20592 | DOI: 10.14744/ijmb.2019.20592

The role of serum acute phase reactant level at prediction of impacted ureteral stone

İsmet Aydın Hazar1, Tuncay Tas2, Cem Tuğrul Gezmiş3, Ersan Arda4, Nusret Can Çilesiz1, Basri Cakiroglu5
1Department of Urology, University of Health Sciences Gaziosmanpaşa Taksim Training and Research Hospital, İstanbul, Turkey
2Department of Urology, Esenyurt University İstanbul Cerrahi Hospital, İstanbul, Turkey
3Department of Urology, Public Hospital of Bitlis, Bitlis, Turkey
4Department of Urology, Trakya University School of Medicine, Edirne, Turkey
5Department of Urology, Hisar Intercontinental Hospital, İstanbul, Turkey

INTRODUCTION: The aim of the study is to estimate whether ureteral stones are impacted by using acute phase reactants
METHODS: Between January 2017 and December 2017, the data of 110 patients
having single ureteral stone receiving medical expulsive therapy (MET) with tamsulosin 0.4 mg/day, diclofenac 75 mg upon analgesic requirement and at least 3 liters fluid per day during one month were evaluated prospectively. Patients underwent ureteroscopy and were divided into two groups according to impaction. The two groups were compared with statistical analysis. The preoperative WBC, RDW, CRP, SED, MPV, NLR values in non-impacted stone group 1(N=59) and impacted group 2 (N=51) were compared.
RESULTS: There was no statistically significant difference in terms of age, stone diameters, body mass index (BMI), grade of hydronephrosis and stone localizations between both groups. WBC, RDW, MPV values differences were statistically significant between groups 1 and 2 (0,035, 0,035 and 0,005 respectively). MPV with a cut off value of 9.55 was defined in group 2 with 66% sensitivity and 62% specificity. There was no statistically significant difference between two groups regarding CRP, Sedimentation and NLR values. (p=0,44, 0,76, 0,54 respectively)
DISCUSSION AND CONCLUSION: Evaluation of serum MPV may predict ureteral stone impaction with the cut-off value of 9.55.

Keywords: Ureteral stone, impacted, mpv, rdw, wbc

Corresponding Author: İsmet Aydın Hazar, Türkiye
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