ISSN  2587-2362  |  E-ISSN  2618-642X

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International Journal of Medical Biochemistry Vitamin D deficiency status in Turkey: A meta-analysis [Int J Med Biochem ]
Int J Med Biochem . Ahead of Print: IJMB-04127 | DOI: 10.14744/ijmb.2019.04127

Vitamin D deficiency status in Turkey: A meta-analysis

MEDİNE ALPDEMİR, Mehmet Fatih Alpdemir
Department of Clinical Biochemistry, Balıkesir State Hospital, Ministry of Health, Balikesir, Turkey

Background: The deficiency of Vitamin D is an significant problem of public health in both developed and developing countries, reported prevalence of 30-80% of children and adults in the worldwide. The purpose of this study was to identified to vitamin D deficiency/insuficiency by used some keywords about frequency of D deficiency/insuficency in the published various article in specific databases in Turkey.
Methods: Pubmed, Dergipark, TUBITAK, Google Scoloor, Google, Scopus Search Engines were used for research. Key words such as; Turkey, vitamin D, serum 25-hydroxyvitamin D, 25(OH)D3, 25(OH)vitamin D, deficiency/insufficiency of vitamin and prevalence were used in the screening process. The Newcastle–Ottawa Quality Assessment Scale was used to assessment the risk of bias in the included studies. The review included prospective and retrospective research studies with healthy, community-based people.
Results: Totally 40 studies with a sample size of 111,582 was included in meta-analysis. The overall prevalence rate of vitamin D deficiency was estimated as 63% (95% CI: 58.9-66.6) for all population. It was observed in this meta-analyses study that vitamin D deficiency was reported as 86.6%(95% CI: 70.2-94.6)for infants, 76%(95% CI: 65.2-84.3) for pregnant women and as 39.8%(95% CI: 38-41.6) for children, and 63.5%(95% CI: 58.8-67.9) for adults. The prevalence rate of vitamin D deficiency for women and man was identified as 64.7% (95% CI: 57.5- 71.2) and 39.5% (95% CI: 31.0- 48.7), respectively.
Conclusions: In the light of the results obtained in this meta-analysis, there is high rate of vitamin D deficiency in Turkey, which varies from 58.9% to 66.6 % in 95% CI. Especially, neonates, pregnant women, women have a higher risk of vitamin deficiency. This meta-analysis is demonstrated that Turkish people should periodically measured their levels of vitamin D.

Keywords: Vitamin D status, Sex, Age, Season, Pregnangy, Covered clothing, Turkish population

Corresponding Author: MEDİNE ALPDEMİR, Türkiye
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