ISSN  2587-2362  |  E-ISSN  2618-642X

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Preoperative evaluation of EDTA-dependent pseudothrombocytopenia before lumbar disc herniation surgery: A case report [Int J Med Biochem ]
Int J Med Biochem . 2018; 1(2): 77-79 | DOI: 10.14744/ijmb.2018.21939

Preoperative evaluation of EDTA-dependent pseudothrombocytopenia before lumbar disc herniation surgery: A case report

Mustafa Sahin1, Unsal Savci2, Havva Hande Keser Sahin3
1Department of Medical Biochemistry, Hitit University, Erol Olcok Education and Research Hospital, Corum, Turkey
2Department of Medical Microbiology, Hitit University, Erol Olcok Education and Research Hospital, Corum, Turkey
3Department of Pathology, Hitit University, Erol Olcok Education and Research Hospital, Corum, Turkey

Ethylenediaminetetraacetic acid-dependent pseudothrombocytopenia (EDTA-PTCP) is an in vitro phenomenon characterized the clustering of platelets following the use of EDTA as an anticoagulant, leading to a decreased analyzer platelet count in a complete blood count (CBC). This report is a description of the case of a 47-year-old male patient admitted to a neurosurgery clinic with the complaints of back and leg pain. A neurological examination and lumbar magnetic resonance imaging revealing extruded disc herniations led to a decision to perform surgery. Thrombocytopenia was detected in the preoperative testing of the patient. The CBC was reanalyzed using citrate. Peripheral blood smears of the patient collected using citrate and EDTA were compared. Thrombocytopenia was not detected in a CBC of the citrated sample and the peripheral smear did not reveal platelet clusters. Pseudothrombocytopenia was considered, as the anamnesis, physical examination findings, and coagulation tests of the patient were not consistent with thrombocytopenia. In conclusion, EDTA-PTCP was diagnosed during the preoperative evaluation of the patient.

Keywords: Citrate, EDTA-dependent pseudothrombocytopenia, peripheral blood smear

Mustafa Sahin, Unsal Savci, Havva Hande Keser Sahin. Preoperative evaluation of EDTA-dependent pseudothrombocytopenia before lumbar disc herniation surgery: A case report. Int J Med Biochem . 2018; 1(2): 77-79

Corresponding Author: Mustafa Sahin, Türkiye
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