Relationship between glycemic control and serum uric acid level in acute myocardial infarction

INTRODUCTION: There are few studies on the relationship between glycemic control and the serum uric acid (SUA) level in acute myocardial infarction (AMI). The aim of this study was to investigate the relationship between glycemic control and SUA level in AMI.
METHODS: This was a retrospective study of patients with AMI who were in the coronary intensive care unit at Bakirkoy Dr. Sadi Konuk Education and Research Hospital between January 2017 and April 2017. Only patients with AMI were included. Age and sex data, as well as total cholesterol, triglycerides, high-density lipoprotein cholesterol (HDL-c), low-density lipoprotein cholesterol (LDL-c), glucose, SUA, and glycated hemoglobin (HbA1c) results were obtained for the study. Patients were classified into 3 groups according to the presence and glycemic control status of diabetes mellitus. Group 1 comprised non-diabetic AMI patients (n=62) and was evaluated as control group. Diabetic patients with good or moderate glycemic control were included in Group 2 (n=35) (<8% HbA1c) and those with poor glycemic control (n=32) (≥8% HbA1c) composed Group 3.
RESULTS: The mean age of the study group was 61 years (SD: 13)(min: 34; max: 92 years). There was no statistically significant difference between groups with regard to the distribution of gender characteristics or the mean values of age, total cholesterol, or LDL-c. In addition, no statistically significant difference was found between the values for HDL-c, triglycerides, and SUA between the study groups. There was no statistically significant difference between the SUA level and the HbA1c level between groups.
DISCUSSION AND CONCLUSION: Additional studies should be done in order to make a definite decision about a potential relationship between glycemic control and SUA level in AMI.